Amanda Peterson, co-star with Patrick Dempsey in “Can’t Buy Me Love,” died at age 43 in her sleep “possibly” July 2, 2015, her body discovered July 5th, from what her father described as sudden “cardiac death associated with sleep apnea.” This is not an isolated case. This OSA killer is out there more than people realize or even care about enough. Death from sleep apnea is preventable. Awareness and vigilance would save lives.

What is OSA?

Obstructive Sleep Apnea is a condition where the individual, usually a snorer, stops breathing momentarily while asleep, and the breath-holding episodes could occur 20 up to more than 100 times during the same night. This causes hypoxemia (dangerously low level of oxygen for the body), sleep impairment, and rest deprivation. The person usually wakes up startled gasping for breath following each episode, because each long pause (20 seconds or longer) in breathing deprives the person of oxygen. The victim is oblivious to all this. As a result, the individual with sleep apnea does not get a satisfying sleep every night and wake up feeling tired and sleepy during the day, some developing a headache and poor concentration while driving or at work. There have been countless deaths during sleep reported among persons with untreated sleep apnea, which triples the risk of death during sleep, but which, fortunately, is preventable with proper treatment.

How common is OSA?

About 9 percent of the adult population in the United States or 30 million have this life-threatening Obstructive Sleep Apnea, and a significant number of them are undiagnosed. Many persons who never woke up from sleep (death usually happens between midnight and 6 AM) were most likely triggered by OSA, where the oxygen deprivation led to suffocation and heart attack/stroke in bed. Twenty five to 45 percent of obese patients have sleep apnea, 72 percent of normal weight patients with type 2 diabetes and 86 percent of obese diabetics have sleep apnea.

What actually happens in sleep apnea?

In some people, especially after middle age and who are obese, the muscles of the upper airways in the back of the throat, like the soft palate (the back end of the roof of the mouth), the uvula (tiny appendage that hangs down), tonsils, adenoids, become flabby and vibrate with the airflow, causing the various classical noises of snoring. These structures could also cave in and out (like a floppy valve) with respiration, blocking the upper airway and causing sleep apnea and oxygen deprivation, leading to suffocation. Besides the anatomical component, there could also be central (neuro-hormonal) factor, especially among obese persons. Weight reduction could help some individuals.

Do all snorers have OSA?

No, not all who snore have sleep apnea, but most of them have it. The only way to be sure is to have a Sleep Study. The check list to find out if one could possibly be a suspect for OSA includes the following questions: Do you snore? Are you a restless sleeper? Do you wake up with a choking sensation at night? Do you wake up feeling tired and sleepy? Does your partner tell you about your breath-holding while asleep? Do you have morning headaches and/or poor memory or concentration? If the answer to any two of the queries above is “yes,” OSA is a great probability.

Could fatigue be due to OSA?

For persons who have unexplained fatigue and daytime sleepiness, it is most probable (after all other medical reasons having been eliminated) that they could have undiagnosed Obstructive Sleep Apnea. Millions are walking around not knowing they have this treacherous condition that is potentially deadly.

What is the impact of OSA ?

Obstructive Sleep Apnea is more common than we think and more dangerous than it is perceived. OSA is a benign condition and easy to treat (not as startling a diagnosis as heart attack or cancer) but left untreated, it could kill faster and surreptitiously like a thief in the night. Otherwise healthy victims are testament to unfortunate preventable premature deaths, wasted lives, which proper prompt diagnosis and treatment could have saved. Healthy people with OSA also have a much higher risk to develop high blood pressure, diabetes, depression, poor mental acuity, poor job performance, driving accidents, heart attack, stroke, Alzheimer’s, and even cancer.

In an article in the June 11, 2013 issue of the Journal of American College of Cardiology, Dr. Apoor Gami, a cardiac electrophysiologist at the Midwest Heart Specialists-Advocate Medical Group in Elmhurst, Illinois, and leader of the study, confirmed the link between sleep apnea and sudden cardiac death. There are many more studies that show the fatalities that resulted from untreated OSA.

How is OSA diagnosed?

To confirm the diagnosis is sleep apnea, a Sleep Testing (Polysomnography) is performed, where the patient sleeps overnight in a Sleep Laboratory, attached to a brain, heart, and blood oxygen monitors, with a video cam showing sleep activity, body movements, etc. All these data are then analyzed the following day. If the patient stops breathing for 10 seconds or more at least five times every hour while asleep, the diagnosis is confirmed.

Are “snore stoppers” or  the “Airing” gadget effective?

“Snore aids” as advertised in the various media, such as Airing gadget, nostril clips, mouth guard, nasal or throat sprays, magnetic wrist bands do not work to stop snoring, much less cure sleep disorders. One contraption, the jaw sling alone, which prevents the jaw from dropping (and snoring) while the person is asleep, does not prevent suffocation from OSA. The manufacturers of these gadgets may one day be sued for false advertisement and negligence in cases of deaths from sleep apnea while using their product.

What is the non-specific therapy?

Weight loss for those who are overweight can minimize the episodes of sleep apnea. Avoidance of sleeping pills, sedatives, and alcohol, all of which increase the frequency and duration of sleep apnea, is most essential. Lying flat on the back induces sleep apnea for a lot of people. This could be avoided by placing a pillow at the back and lying on the side. But these are only helpful aids, not really treatment.

What is the specific treatment for OSA?

Before treatment could be prescribed, a Sleep Study is needed to confirm the diagnosis first and also to titrate and measure the effective positive pressure needed to keep the airway open for each individual patient. The gold standard in the management of OSA is with the use of Continuous Positive Airway Pressure (CPAP), which has a reinforced tubing connected a mask or a nasal pillow. This portable machine with a humidifier pushes room air with a prescribed positive pressure derived from the Sleep Study through a masked (over the mouth and nose) or via a nasal pillow (through the nose only) into the breathing pipe of the person, preventing the collapse of the breathing passage behind the throat, and pushing in humidified air into the lungs for good effective ventilation at a normal rate. While most CPAP machines need to be connected to an electric wall outlet for power, there are a couple of brand which come with a portable rechargeable battery option, to be used while on board a plane, a boat or for camping.

When is surgery needed?

Surgery removes tissues, like nasal polyps, adenoids, tonsils, and any oro-pharyngeal deformities that causes obstruction to airflow. One of them is called uvulopalatopharyngoplasty, which excises tissues at the back of the throat. The success rate is low, between 30-60 percent and it is hard to know which patients will benefit from it, its side effects and eventual outcome. The others are tracheostomy (creating a hole in the windpipe for those with severe obstruction, which is not too common), surgical reconstruction for those with deformities, and surgery to treat diet-and-exercise-resistant obesity, which contributes to sleep apnea. Fortunately, the use of the CPAP machine has been found to be most effective in managing practically all Obstructive Sleep Apnea. Unbelievable at it may seem, the use of CPAP is really comfortable and unobtrusive, and provides a restful sleep and a great sense of security that some users even get “addicted” to it.

Indeed, having sleep apnea is a warning and nothing to snore about.

***

Philip S. Chua, MD, FACS, FPCS, Cardiac Surgeon Emeritus in Northwest Indiana and chairman of cardiac surgery from 1997 to 2010 at Cebu Doctors University Hospital, where he holds the title of Physician Emeritus in Surgery, is based in Las Vegas, Nevada. He is a Fellow of the American College of Surgeons, the Philippine College of Surgeons, and the Denton A. Cooley Cardiovascular Surgical Society. He is the chairman of the Filipino United Network – USA,  a 501(c)(3) humanitarian foundation in the United States. Email: [email protected]

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